ANALYSIS OF DRUGS IN PHARMACOKINETIC STUDIES
Abstract
A review of sensitive and specific analytical methods used in studying the pharmacokinetics of drugs is provided. The advantages and limitations of using enzyme immunoassay, a method of high-performance liquid chromatography with fluorescence and mass spectrometric detection, are shown. The use of one or another method in assessing the pharmacokinetics of drugs in each specific case is determined by the structure of the compound being studied and the equipment of the laboratory.
Keywords
Fluorescence and mass spectrometric detection, liquid chromatography, method, enzyme immunoassay, pharmacokinetics.
References
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