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Vol. 11 No. 04 (2024)
International Multidisciplinary Journal for Research & Development (IMJRD)

Articles

MODERN METHODS OF TREATMENT OF VARICOSE VEINS OF THE LOWER EXTREMITIES (Literature review)

Published 2024-04-19

  • B.B.Mirzaev,Sh.H.Kosimov

B.B.Mirzaev,Sh.H.Kosimov
Fergana Medical Institute of Public Health

Abstract

Varicose veins of the lower extremities (LVLD) is the most common pathology of peripheral vessels [ 1, 5, 17 ].

Modern data indicate that the detection rate of chronic venous diseases (CVD) among the adult population is at least 25% [ 4, 15, 18 ]. A number of studies also present higher figures, indicating the prevalence of the disease with a frequency of up to 50% or more [ 2, 9 ].

Many studies have been devoted to the study of the pathogenesis of varicose veins, and to date, an impressive amount of knowledge has been accumulated about the events accompanying varicose vein transformation at different levels, including genetic and molecular changes [ 8, 10 ]. Factors influencing this process include changes in hemodynamics - a decrease in laminar blood flow velocity and the appearance of turbulent blood flow, an increase in venous pressure and associated stretching of the vein walls, hypoxia, oxidative stress, endothelial activation and inflammation [ 6, 7, 8, eleven ].

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