FEATURES OF PATHOGENESIS, CLINICAL PICTURE AND DIAGNOSIS OF CO-INFECTION OF THE LIVER WITH HEPATITIS B AND C VIRUSES

Abstract

In the course of the infectious process of combined HBV/HCV - etiology has been observed indirect evidence for mutual inhibition of the two hepatotropic viruses. The severity of clinical, laboratory and histological changes in the liver in latent forms is mainly due to HCV infection characterized by the speed of seroconversion of HBeAg/HBeAb and the disappearance of HBV Blood DNA from the patient against the background of the continuing persistence of HCV. Isolation of different variants of the course of mixed hepatitis is uninformative in relation to the outcome and prognosis of the disease. At the same time, a thorough assessment of the activity of viral replication of both pathogens determines the choice of rational therapy.