DEVELOPMENT OF A RAT MODEL OF DIABETIC FEMORAL PHLEGMON FOR EVALUATING THE EFFECTIVENESS OF TRADITIONAL AND INNOVATIVE TREATMENT METHODS
Abstract
Models on various experimental animals remain the most convenient tool for studying the pathophysiological mechanisms of various diseases. One of the simplest ways to create a model of diabetes mellitus and hyperglycemia in animals is partial or complete pancreatectomy. Also, chemical agents that cause damage to pancreatic beta cells, which leads to the development of diabetes, are used to model diabetes mellitus. In this context, such diabetogenic substances as streptozotocin, alloxan, pirinuron, ditizon, dialuric acid and others are used.
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