PHYSIOLOGICAL AND BIOCHEMICAL CHANGES IN THE LIVER UNDER THE INFLUENCE OF STRESS FACTORS
Abstract
The liver is a central organ affected by various stressors including environmental toxins, psychological pressure, and poor dietary habits. These stressors activate complex physiological and biochemical pathways leading to oxidative stress, mitochondrial dysfunction, inflammation, and metabolic disruptions. Psychological stress affects the liver through hormonal and nervous system responses, while unhealthy diets exacerbate liver damage via increased lipid accumulation and insulin resistance. The synergistic effects of these stressors contribute to liver diseases such as MASLD and NASH. Protective interventions, including antioxidant-rich diets, are essential to mitigate stress-induced liver damage.
Keywords
liver, stress, oxidative stress, psychological stress, fatty liver disease.
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