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Vol. 12 No. 05 (2025)
International Multidisciplinary Journal for Research & Development

Articles

STUDYING THE EFFECT OF MEDICINAL PLANT PREPARATIONS ON ANTIGEN COMPETITION IN THE IMMUNE RESPONSE

Published 2025-06-06

  • Teshaboyev Azizbek Muhammadaliyevich

Teshaboyev Azizbek Muhammadaliyevich
Fergana Medical Institute of Public Health Fergana, Uzbekistan

Abstract

White mice were divided into 8 groups to study the effect of herbal preparations on antigen competition in white mice. When mice are injected with a dominant antigen (EL) 4 days before EB immunization, a dramatic (4.7-fold) suppression of the immune response to EB occurs, meaning that the dominant antigen suppresses the body's immunological response to EB. In mice pretreated with EL, the number of nucleated spleen cells was reduced by 1.3 compared to controls. Gulzor 17-Doctor Ali 6 NSC increases 2.3 times when EL is taken together with "Hepar Neo" balm; Gulzor 17-Doctor Ali 6 "Hepar Neo" balm combined with EB increases the number of AJ by 3.1 times compared to group 2. Similar results were obtained when the number of AJS significantly increased as a result of the introduction of herbal preparations: (EL + Balsam Gulzor) + EB - 1.9 times, EL (EB + Balsam Gulzor) - 2.7 times, (EL + Detoxioma ) + EB - 1.7 times and EL+(EB+Detox) - 1.9 times.

Keywords

Herbal medicinal preparations, immune response, antigen, phagocytes, immunization.

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