CAUSES OF DRUG-RESISTANT TUBERCULOSIS IN FERGANA REGION

Authors

  • Tojiboyev D. Central Asian Medical University

Keywords:

tuberculosis, TB, drug resistance, MDR, delayed diagnosis, incorrect treatment, treatment compliance, migration, poverty, socioeconomic factors, pharmacotherapy, TB prevention.

Abstract

This article provides an in-depth analysis of the key causes leading to the emergence of drug-resistant (MDR – multidrug-resistant) tuberculosis (TB) in the Fergana region. It presents statistical data and detailed district-level breakdowns illustrating the wide spread of the disease. Medical, socioeconomic, and migration-related factors contributing to the development of drug resistance are highlighted separately [1][2]. The paper also develops recommendations based on observed treatment non-compliance, self-medication practices, delayed healthcare seeking, and structural issues in the health system [3][5]. These recommendations aim to increase public awareness, strengthen psychological and social support, introduce electronic monitoring, and enhance preventive measures.

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References

Ministry of Health of the Republic of Uzbekistan. “2023 Tuberculosis Report.” Tashkent, 2024.

World Health Organization. Global Tuberculosis Report, 2023. Geneva: WHO.

Fergana Regional Health Department. “Regional Epidemiological Data.” Fergana, 2023.

Medical Academic Literature: Phthisiology. Textbook. Tashkent Medical Publishing, 2022.

Karimov K., Ismoilova Sh. “Problems of Drug Resistance in Tuberculosis.” Tashkent, 2021.

WHO. Companion Handbook to the WHO Guidelines for the Programmatic Management of Drug-Resistant Tuberculosis. Geneva, 2014.

Yuldashev A., Mahmudova D. “Analytical Data on Drug-Resistant TB in Uzbek Regions.” Medical Journal, 2023(2): 45–52.

WHO Europe. “Action Plan for the Prevention and Control of M/XDR-TB in the WHO European Region 2011–2015.” Copenhagen, 2011.

Aziz M.A., Wright A., Laserson K., et al. “Epidemiology of Anti-TB Drug Resistance.” The Lancet, 2006; 368(9553): 2142–2154.

Dara M., Acosta C.D., Melchers N.V.S., et al. “TB Control in Prisons: Current Status and Research Gaps.” Int J Infect Dis, 2015; 32: 111–117.

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Published

2025-07-26

How to Cite

Tojiboyev D. (2025). CAUSES OF DRUG-RESISTANT TUBERCULOSIS IN FERGANA REGION. International Multidisciplinary Journal for Research & Development, 12(07). Retrieved from https://www.ijmrd.in/index.php/imjrd/article/view/3588

Issue

Vol. 12 No. 07 (2025): International Multidisciplinary Journal for Research & Development

Section

Articles

License

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.