HEMOLITIC DISEASES IN INFANTS

Abstract
This article discusses the causes of hemolytic disease in infants, the mechanisms of development, clinical manifestations, diagnosis and treatment methods. The main cause of the disease is immunological imbalance between the mother and child, in particular, the discrepancy between the Rh factor and AB0 blood groups. The study provides information about the clinical signs of hemolytic disease, including jaundice, hemolytic anemia, liver and spleen enlargement, as well as its complications. Attention is also paid to modern diagnostic and treatment methods: phototherapy, blood transfusion, drug treatment and resuscitation measures are analyzed. Of the preventive measures, the effectiveness of the use of anti-D immunoglobulin in preventing Rh incompatibility is especially emphasized. The scientific and practical significance of this work is that it develops recommendations for the prevention, timely detection and treatment of hemolytic disease in infants. This will serve to improve children's health in the field of pediatrics and neonatology, and raise a healthy generation.
Keywords
hemolytic disease of newborns, rhesus incompatibility, AB0 system, immunological conflict, hemolysis, jaundice (neonatal icterus), hemolytic anemia, anti-D immunoglobulin, phototherapy, blood transfusion, neonatology, prevention.
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