THE MOST ACCESSIBLE DIAGNOSTIC METHODS FOR TUBERCULOSIS IN HIV-INFECTED PATIENTS
Keywords:
HIV infection, tuberculosis, co-infection, diagnostics, GeneXpert MTB/Rif, drug resistance, latent tuberculosis, Quantiferon test.Abstract
This article addresses the pressing medical and social issue of HIV and tuberculosis co-infection. The objective of the study was to examine the structure and informativeness of various diagnostic methods for tuberculosis in HIV-infected individuals. The research included 50 patients with both HIV and tuberculosis who received treatment at the Andijan Regional Center for Phthisiology and Pulmonology from 2022 to 2024. A range of traditional and modern diagnostic methods were employed, such as the Mantoux test, Diaskintest, Quantiferon test, GeneXpert MTB/Rif, and BACTEC MGIT 960 liquid culture. The results indicated that infiltrative tuberculosis was the predominant clinical form , and the GeneXpert MTB/Rif test was identified as the most sensitive diagnostic method, yielding positive results in 34 patients. The conclusion emphasizes that modern bacteriological and immuno-genetic methods enable the rapid detection of drug resistance, which is crucial for administering effective treatment.
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