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Vol. 12 No. 10 (2025)
International Multidisciplinary Journal for Research & Development

Articles

THE MOST ACCESSIBLE DIAGNOSTIC METHODS FOR TUBERCULOSIS IN HIV-INFECTED PATIENTS

Published 2025-10-10

  • Abdumanapova Ranokhon Kakhramanovna

Abdumanapova Ranokhon Kakhramanovna
Department of Phthisiology and Pulmonology, Microbiology, Immunology and Virology. Andijan State Medical Institute, Republic of Uzbekistan

Abstract

This article addresses the pressing medical and social issue of HIV and tuberculosis co-infection. The objective of the study was to examine the structure and informativeness of various diagnostic methods for tuberculosis in HIV-infected individuals. The research included 50 patients with both HIV and tuberculosis who received treatment at the Andijan Regional Center for Phthisiology and Pulmonology from 2022 to 2024. A range of traditional and modern diagnostic methods were employed, such as the Mantoux test, Diaskintest, Quantiferon test, GeneXpert MTB/Rif, and BACTEC MGIT 960 liquid culture. The results indicated that infiltrative tuberculosis was the predominant clinical form , and the GeneXpert MTB/Rif test was identified as the most sensitive diagnostic method, yielding positive results in 34 patients. The conclusion emphasizes that modern bacteriological and immuno-genetic methods enable the rapid detection of drug resistance, which is crucial for administering effective treatment.

Keywords

HIV infection, tuberculosis, co-infection, diagnostics, GeneXpert MTB/Rif, drug resistance, latent tuberculosis, Quantiferon test.

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References

  1. 1. S. Yu. Degtyareva, V. N. Zimina, A. V. Pokrovskaya, G. V. Volchenkov - Safety and Efficacy of Multidrug-Resistant Tuberculosis Therapy in Patients with Different HIV Status. Tuberculosis and Lung Diseases Vol. 100, No. 1, 2022, pp. 33-40
  2. 2. R. S. ALZHANOV, A. V. PYATIBRATOVA, D. V. KRASNOV, D. V. KAPUSTIN, S. V. ANUFRIEV - Clinical and Laboratory Features of COVID-19 in Patients with Co-Infection with HIV and Tuberculosis. Tuberculosis and Lung Diseases Vol. 100, No. 4, 2022, 14-20 pp
  3. 3. T. V. Myakisheva, I. S. Lapshina - Tuberculous meningitis in HIV-positive and HIV-negative patients. Tuberculosis and Lung Diseases Vol. 100, No. 6, 2022
  4. 4. D. B. Fayzullaeva, N. N. Parpieva, M. A. Khakimov. Diagnosis and treatment of tuberculous lymphadenopathy in HIV-infected patients. Tashkent, 2021
  5. 5. M. V. Sinitsyn, S. V. Bykov, M. N. Reshetnikov, I. S. Aralova, A. G. Antipov - Endoscopic diagnosis of bronchial tuberculosis in patients with pulmonary tuberculosis with different HIV status. Tuberculosis and Lung Diseases Vol. 100, No. 7, 2022, 28-33 pages
  6. 6. A.A. KHOLODOV, E.O. BRYUKHACHEVA, M.V. PRIMKULOVA, M.B. LAVRYASHINA, T.V. PYANZOVA Clinical efficacy of complex probiotic therapy for intestinal dyspepsia syndrome in patients with multidrug-resistant tuberculosis combined with HIV infection Tuberculosis and Lung Diseases Vol. 100, No. 7, 2022, 34-40 pages
  7. 7. O.P. FROLOVA, T.I. SHARKOVA, O.V. BUTYLCHENKO, L.P. SEVEROVA, N.G. ERSHOVA - Optimization of tuberculosis detection and prevention in patients with HIV infection Tuberculosis and Lung Diseases Vol. 101, No. 4, 2023, 29-33 pp
  8. 8. E. V. KULCHAVENYA, S. Yu. SHEVCHENKO, O. S. STRELTSOVA, V. N. KRUPIN, A. A. BARANCHUKOVA - Genital tuberculosis in men living with HIV. Tuberculosis and Lung Diseases Vol. 101, No. 6, 2023, 28-33 pp
  9. 9. N. A. SOSOVA, T. A. ZADREMAILOVA, N. M. KONOVALOVA, A. V. ABRAMCHENKO, M. I. ROMANOVA, A. I. GAYDA, A. G. SAMOILOVA - Treatment results for patients with drug-resistant tuberculosis (MDR, pre-XDR, XDR) and HIV infection in the Stavropol Territory. Tuberculosis and Lung Diseases Vol. 102, No. 3, 2024, 64-70 pp
  10. 10. E.S. NIKITINA, O.S. ILYINA, O.D. BARONOVA - Use of dispersible combination drugs in chemotherapy of drug-susceptible tuberculosis: results of an observational study. Tuberculosis and Lung Diseases Vol. 102, No. 4, 2024, 56-62 pp
  11. 11. A.A. GERASIMOVA, A.A. VYAZOVAYA, M.Yu. MAISKAYA, A.M. PANTELEEV, I.V. MOKROUSOV - Molecular genetic characteristics of Mycobacterium tuberculosis isolates from patients with HIV-associated tuberculosis. Tuberculosis and Lung Diseases Vol. 102, No. 5, 2024, 70-75 pp
  12. 12. Chumachenko G.V., Babaeva I.Yu., Avdeeva M.G. - The relevance of the problem of co-infection of HIV and tuberculosis in modern epidemiological conditions. Epidemiology and Infectious Diseases. 2016; 21(6) DOI: https://doi.org/10.17816/EID40932 Problematic articles, 304-312 pp

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