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Vol. 12 No. 11 (2025)
International Multidisciplinary Journal for Research & Development

Articles

RETINAL MICROCIRCULATION DISORDERS IN PATIENTS WITH HYPERTENSIVE DISEASE: A MORPHOMETRIC APPROACH

Published 2025-11-11

  • Yuldasheva N.M., Boboeva R. R., Rakhmatova M. R.

Yuldasheva N.M., Boboeva R. R., Rakhmatova M. R.
2nd-year Master’s student, Department of Ophthalmology,PhD, Associate Professor, scientific supervisor,PhD, Associate Professor, scientific consultant,Bukhara State Medical Institute named after Abu Ali ibn Sino, Uzbekistan

Abstract

This study aimed to investigate the morphometric parameters of retinal vessels in patients with hypertensive retinopathy. A total of 60 patients who were referred to the Bukhara Branch of the Republican Specialized Scientific and Practical Medical Center for Eye Microsurgery were included in the study. The patients underwent a comprehensive examination using visual acuity testing, tonometry, A-scan ultrasonography, biomicroscopy, ophthalmoscopy, fundus photography, and optical coherence tomography (OCT).

The results showed that most patients exhibited arteriolar narrowing, venular dilation, arteriovenous ratio disruption, as well as signs of vasospasm and sclerotic changes in the vessel walls. Changes in the optic nerve head and the retinal nerve fiber layer (RNFL) were manifested as mild optic disc cupping and thinning of the RNFL in the superior and inferior quadrants. Morphometric parameters of the retinal vessels were significantly correlated with the severity and duration of hypertension (p < 0.05).

Morphometric analysis of retinal vessels using fundus photography and OCT is a reliable and objective method for assessing microcirculatory alterations in hypertensive retinopathy. These methods can be utilized for early diagnosis, monitoring disease progression, and evaluating the effectiveness of therapeutic interventions.

Keywords

retinal vessels, morphometric parameters, optical coherence tomography (OCT), fundus photography, microcirculation, hypertensive retinopathy.

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References

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