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MUSCULAR DYSTROPHIES: CONTEMPORARY VIEWS ON THE DEVELOPMENT OF THE DISEASE

Abstract

 Muscular dystrophies are hereditary disorders primarily affecting skeletal muscles. Several distinct types of the disease are recognized, the majority of which are caused by mutations in genes encoding structural or regulatory proteins of muscle cells. Today, modern genetic approaches to therapy have demonstrated promising results.

Keywords

Muscular dystrophies, Duchenne, Becker, Myotonic dystrophy

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References

  1. Martina Rimoldi. Myotonic dystrophies: an update on clinical features, molecular mechanisms, management, and gene therapy. Neurological Sciences, 2024.
  2. Camille Bouchard, Jacques P. Tremblay. Limb–Girdle Muscular Dystrophies: Classification and Therapies. Clinical Medicine, 2023.
  3. Sabrina Lucchiari. Myotonic dystrophies: an update on clinical features, molecular mechanisms, management, and gene therapy. Neurological Sciences, 2025.
  4. Sokolovskaya M.Ya., Makartseva E.S. A clinical case of familial Duchenne muscular dystrophy. Mother and Child Journal, 2022.
  5. Tsarkova S.A., Ushakova R.A. Progressive Duchenne–Becker muscular dystrophy: diagnostic challenges. Pediatrics, Vol. 19, 2020.

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