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Vol. 12 No. 12 (2025)
International Multidisciplinary Journal for Research & Development

Articles

CLINICAL PROCESS OF CHANGES IN THE GASTROINTESTINAL TRACT IN POST-CHOLECYSTECTOMY SYNDROME

Published 2025-12-16

  • Dadabayeva Zoxida Ibrokhimjan kizi

Dadabayeva Zoxida Ibrokhimjan kizi
Assistant of the Department of Rehabilitology, Sports Medicine, Traditional Medicine and Physical Education. Andijan State Medical Institute Andijan, Republic of Uzbekistan.

Abstract

Post-cholecystectomy syndrome (PCS) represents a complex clinical condition affecting 10-40% of patients following gallbladder removal, characterized by persistent or recurrent gastrointestinal symptoms. This review examines the pathophysiological mechanisms underlying gastrointestinal tract alterations in PCS, including bile acid dysregulation, sphincter of Oddi dysfunction, and intestinal microbiota disturbances. Understanding these clinical processes is essential for developing targeted therapeutic strategies and improving patient outcomes following cholecystectomy.

Keywords

post-cholecystectomy syndrome, bile acids, gastrointestinal tract, cholecystectomy complications, sphincter of Oddi dysfunction

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References

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