MODERN PERSPECTIVES ON NECROTIZING ENTEROCOLITIS IN CHILDREN: ETIOLOGY, PATHOGENESIS, DIAGNOSIS, AND TREATMENT.

Authors

  • Raufova Nasiba Shukhratovna Intern Lecturer of the Department of Preclinical Sciences, Asia International University

Keywords:

Necrotizing enterocolitis, premature infant, intestinal necrosis, neonatal sepsis, parenteral nutrition.

Abstract

Necrotizing enterocolitis (NEC) is a severe and life-threatening intestinal disease that occurs in newborns, particularly in premature infants. The condition is characterized by inflammation, ischemia, and necrosis of the intestinal wall. This article provides a comprehensive overview of the etiological factors of NEC, the mechanisms of its pathogenesis, clinical manifestations, diagnostic approaches, and modern principles of treatment. In addition, preventive measures and the possible outcomes of the disease are analyzed.

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References

Cloherty J.P., Eichenwald E.C., Hansen A.R., Stark A.R. Manual of Neonatal Care. 8th ed. Philadelphia: Wolters Kluwer; 2017.

Kliegman R.M., St. Geme J.W., Blum N.J., Shah S.S., Tasker R.C., Wilson K.M. Nelson Textbook of Pediatrics. 21st ed. Philadelphia: Elsevier; 2020.

Fanaroff A.A., Martin R.J., Walsh M.C. Fanaroff and Martin’s Neonatal-Perinatal Medicine. 11th ed. Philadelphia: Elsevier; 2020.

Neu J., Walker W.A. Necrotizing enterocolitis. New England Journal of Medicine. 2011;364(3):255–264.

Niño D.F., Sodhi C.P., Hackam D.J. Necrotizing enterocolitis: new insights into pathogenesis and mechanisms. Nature Reviews Gastroenterology & Hepatology. 2016;13(10):590–600.

World Health Organization (WHO). Guidelines on optimal feeding of low birth-weight infants. Geneva: WHO; 2011.

American Academy of Pediatrics. Necrotizing enterocolitis in newborns: clinical report. Pediatrics. 2012;129(2):e651–e659.

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Published

2026-03-24

How to Cite

Raufova Nasiba Shukhratovna. (2026). MODERN PERSPECTIVES ON NECROTIZING ENTEROCOLITIS IN CHILDREN: ETIOLOGY, PATHOGENESIS, DIAGNOSIS, AND TREATMENT. International Multidisciplinary Journal for Research & Development, 13(03), 618–620. Retrieved from https://www.ijmrd.in/index.php/imjrd/article/view/5379