CLINICAL-ANAMNESTIC AND PATHOMORPHOLOGICAL CHARACTERISTICS OF ESOPHAGEAL MALIGNANCIES AMONG THE POPULATION OF THE FERGANA VALLEY
Abstract
Background: The Fergana Valley is identified as a high-risk region for esophageal cancer (EC) due to a combination of unique dietary habits, environmental factors, and lifestyle choices.
Objectives: This study aims to analyze the clinical-anamnestic patterns and pathomorphological features of esophageal malignancies in this specific population to improve early diagnosis and prevention strategies.
Methods: A retrospective analysis of clinical records and biopsy reports from regional oncological centers was conducted, focusing on patients diagnosed between 2018 and 2026.
Results: The majority of cases are diagnosed at advanced stages (III-IV). Squamous cell carcinoma remains the dominant histological type (88%). Key anamnestic triggers include the consumption of "nasway," hot beverages, and nutritional deficiencies.
Conclusion: Targeted screening programs focusing on the specific risk factors of the Fergana Valley population are essential to reduce the mortality associated with esophageal malignancies.
Keywords
Esophageal Cancer, Fergana Valley, Squamous Cell Carcinoma, Nasway, Pathomorphology, Clinical-Anamnestic Analysis.
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