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Vol. 13 No. 4 (2026)
International Multidisciplinary Journal for Research & Development

Articles

BREAKTHROUGH THERAPIES IN TYPE 2 DIABETES: ADVANCED ROLE OF GLP-1 RECEPTOR AGONISTS AND SGLT2 INHIBITORS

Published 2026-04-20

  • Ergasheva Gulshan Tokhirovna

Ergasheva Gulshan Tokhirovna
Assistant of the Department of Clinical Sciences Asian International University, Bukhara, Uzbekistan

Abstract

Type 2 diabetes mellitus (T2DM) is a global health challenge characterized by chronic hyperglycemia and associated complications. Recent therapeutic breakthroughs, particularly GLP-1 receptor agonists and SGLT2 inhibitors, have transformed diabetes management. These agents not only reduce blood glucose levels but also provide cardiovascular and renal protection. This article provides a comprehensive review of their mechanisms, clinical efficacy, combination therapy, and future perspectives in modern diabetes care.

Keywords

Type 2 diabetes mellitus, GLP-1 receptor agonists, SGLT2 inhibitors, semaglutide, tirzepatide, cardiovascular protection, renal protection, incretin therapy

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