Skip to main navigation menu Skip to main content Skip to site footer

Vol. 10 No. 12 (2023)
International Multidisciplinary Journal for Research & Development

Articles

PROPARGYL ESTER OF DISUBSTITUTED PHENOXYACETIC ACID

Published 2023-12-25

  • Khojimatova Shakhnoza Rakhmatalievna

Khojimatova Shakhnoza Rakhmatalievna
Doctorate of Andijan Institute of Mechanical Engineering

Abstract

The propargyl ester of disubstituted phenoxyacetic acid is a chemical compound that consists of a phenoxyacetic acid molecule with two substituents attached to the aromatic ring, and an ester group attached to the carboxyl group of the acid. Additionally, the ester group contains a propargyl functional group. The solvents used were ethyl acetate, ethyl alcohol, hexane, acetone, benzene, and toluene. The structure of the synthesized compounds was reliably analyzed using modern IR, 1H and 13C NMR spectroscopy.

Keywords

Propargyl ester, phenoxyacetic acid, ethyl acetate, ethyl alcohol, hexane, acetone, benzene, and toluene.

DOWNLOAD PDF CERTIFICATE

References

  1. Kothare S, Kluger G, Sachdeo R, Williams B, Olhaye O, et al. Dosing considerations for rufinamide in patients with Lennox-Gastuat syndrome: phase III trial results and the real world clinical data // Seizure. -2017.-Vol 47. -P. 25-33.
  2. Menendez C, Gau S, Lherbet C, Rodriguez F, Inard C, et al. Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents //Eur J Med Chem. -2011.-Vol. 46. -P. 5524-5531.
  3. Wang Q, Zhang J, Damu GLV, Wan K, Zhang HZ, et al. Synthesis and biological activities of thio-triazole derivatives as novel antibacterial and antifungal agents // Sci China Chem. -2012. -Vol. 55. –P. 2134-2153.
  4. Nadeem H, Mohsin M, Afzaal H, Riaz S, Zahid A, et al. Synthesis and in vitro biological activities of 4,5-disubstituted 1,2,4-triazol-3-thols //Adv Microbiol. 2013. - Vol. 3. -P. 366-375.
  5. Asif M. A mini review on antimalarial activities of biologically active substituted triazole derivatives //Int J Adv Res Chem Sci. -2014 Vol. 1 22-28.
  6. Li L, Zhang Z. Development and applications of the copper-catalyzed azide-alkyne cycloaddition (CUAAC) as a bioorthogonal reaction //Molecules-2016.-Vol. 21. – P. 1-22
  7. Martinelli M., Milcent T., Ongeri S., Crousse B. Synthesis of new triazole-based trifluoromethyl scaffolds // Beilstein Journal of Organic Chemistry. -2008. -Vol. 4. No. 19. –P. 1–4.
  8. Abdugafurov I.A., Makhsumov A.G., Madikhanov N.1,3-Dipolar cycloprine compound of phenylazide to 3-(2-R-phenoxy)-1-propines and IR, PMR spectra of 1,2,3-triazole isomers // Journal of Org.chem.-1987. -Vol. 23, - No. 9. - P. 1986-1990.
  9. Аbdugafurov I.A., Qirgizov F.B., Ortikov I.S. Synthesisof 1,2,3-triazolederivativesbasedonpropargylesterofasaturatedsinglebasiccarbonic acid and para-azidobenzoic acid // European Journal of Chemistry-2021. -№ 12 (1). -P. 13-17.

Downloads

Download data is not yet available.