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Vol. 12 No. 04 (2025)
International Multidisciplinary Journal for Research & Development

Articles

CORTISOL LEVELS AND ANXIETY SEVERITY IN ADOLESCENTS WITH NEUROCIRCULATORY DYSTONIA

Published 2025-04-14

  • Abdulkhakova R.M.

Abdulkhakova R.M.
Andijan state medical institute Uzbekistan, Andijan

Abstract

 This study examines the relationship between serum cortisol levels and the severity of anxiety in adolescents with neurocirculatory dystonia (NCD). The results demonstrate significantly higher cortisol concentrations in the NCD group, accompanied by elevated scores on the State-Trait Anxiety Inventory. These findings suggest a potential role of hypothalamic-pituitary-adrenal (HPA) axis hyperactivity in the emotional and autonomic dysregulation observed in NCD.

Keywords

neurocirculatory dystonia, cortisol, anxiety, adolescents, HPA axis.

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References

  1. 1.Алексеев В.В., Жуков А.Н. Нейроциркуляторная дистония: руководство для врачей. — М.: ГЭОТАР-Медиа, 2014.
  2. Пальчун В.Т. Руководство по клинической неврологии. Том 2. — М.: Медицина, 2012.
  3. Громова О.А., Смирнов А.А., Шестакова И.Н. Гипоталамо-гипофизарно-надпочечниковая система и стресс: патогенетические и клинические аспекты. // Вестник РАМН. — 2017. — №3. — С. 45–52.
  4. Мельниченко Г.А. Эндокринология подросткового возраста. — М.: МЕДпресс-информ, 2019.
  5. Spielberger, C.D., Gorsuch, R.L., & Lushene, R.E. (1970). Manual for the State-Trait Anxiety Inventory (STAI). Palo Alto, CA: Consulting Psychologists Press.
  6. Kudielka, B.M., Hellhammer, D.H., & Wüst, S. (2009). Why do we respond so differently? Reviewing determinants of human salivary cortisol responses to challenge. Psychoneuroendocrinology, 34(1), 2–18.
  7. Gunnar, M.R., & Quevedo, K. (2007). The neurobiology of stress and development. Annual Review of Psychology, 58, 145–173.
  8. Burke, H.M., Davis, M.C., Otte, C., & Mohr, D.C. (2005). Depression and cortisol responses to psychological stress: A meta-analysis. Psychoneuroendocrinology, 30(9), 846–856.
  9. McEwen, B.S. (2007). Physiology and neurobiology of stress and adaptation: central role of the brain. Physiological Reviews, 87(3), 873–904.
  10. Young, E.A., Abelson, J.L., & Cameron, O.G. (2005). Anxiogenic effects of the CRH1 receptor antagonist R121919 in humans: Relationship to HPA axis function. Psychoneuroendocrinology, 30(5), 525–534.
  11. Левченко Ю.Н., Лисицын Ю.П. Психическое здоровье и адаптационные реакции у подростков. // Журнал неврологии и психиатрии им. С.С. Корсакова. — 2021. — Т. 121, № 4. — С. 75–81.
  12. Сапожников М.Г. Нейроэндокринные механизмы тревожных расстройств у подростков. // Российский психиатрический журнал. — 2020. — № 2. — С. 43–48.

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