THE ROLE OF PROCALCITONIN AS A MARKER IN CHRONIC RHEUMATIC HEART DISEASE

Authors

Turayev Telmon Temirovich,Bobojonov Khurshid Jumaniyozovich Bukhara State Medical Institute

Keywords:

chronic rheumatic heart disease, procalcitonin, biomarkers, inflammation, children. Relevance

Abstract

Chronic rheumatic heart disease (CRHD) remains one of the leading causes of acquired heart defects in children and adolescents in developing countries. Procalcitonin (PCT), a peptide precursor of calcitonin, is a sensitive marker of systemic inflammatory response and may reflect the activity of rheumatic inflammation and secondary bacterial infection. Determining serum procalcitonin levels may improve the early diagnosis, prognosis, and management of CRHD during exacerbations.

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References

WHO. Rheumatic Fever and Rheumatic Heart Disease: Technical Report. Geneva, 2021.

Shabalov N.P. Pediatrics: textbook. St. Petersburg: SpetsLit, 2020.

Lakkireddy D.R. et al. Procalcitonin as a Marker of Cardiac Inflammation. J Clin Cardiol, 2022;15(4):213‒220.

MOH RF. Clinical Guidelines for Rheumatic Heart Disease, 2020.

Braunwald E. Heart Disease: Textbook of Cardiovascular Medicine. 12th ed., 2021.

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Published

2025-11-15

How to Cite

Turayev Telmon Temirovich,Bobojonov Khurshid Jumaniyozovich. (2025). THE ROLE OF PROCALCITONIN AS A MARKER IN CHRONIC RHEUMATIC HEART DISEASE. International Multidisciplinary Journal for Research & Development, 12(11), 250–251. Retrieved from https://www.ijmrd.in/index.php/imjrd/article/view/4021