Skip to main navigation menu Skip to main content Skip to site footer

Vol. 13 No. 01 (2026)
International Multidisciplinary Journal for Research & Development

Articles

THE RELATIONSHIP BETWEEN ANEMIA AND GYNECOLOGICAL DISEASES

Published 2026-01-16

  • Ne'matova Zubaydakhon Mansurbek kizi, Khadjayeva Dilnoza Bobirovna

Ne'matova Zubaydakhon Mansurbek kizi, Khadjayeva Dilnoza Bobirovna
Kokand University, Andijan Branch

Abstract

Anemia remains one of the most prevalent hematological disorders worldwide and disproportionately affects women of reproductive age. Gynecological diseases are recognized as major contributing factors to the development and persistence of anemia, primarily through chronic blood loss, inflammation, and hormonal disturbances.

The aim of this study was to analyze the relationship between anemia and gynecological diseases and to review current approaches to diagnosis and management based on recent clinical evidence. A narrative review of the literature was conducted using international databases, including PubMed, Scopus, Web of Science, and Google Scholar. Studies published between 2015 and 2024 were analyzed, focusing on etiological factors, pathophysiological mechanisms, and therapeutic strategies related to anemia in women with gynecological disorders.

The reviewed studies demonstrated that abnormal uterine bleeding, uterine fibroids, endometriosis, adenomyosis, and chronic inflammatory gynecological conditions are strongly associated with iron deficiency anemia. Chronic menstrual blood loss and inflammatory processes were identified as the primary mechanisms leading to reduced hemoglobin levels. Early diagnosis and integrated management combining treatment of the underlying gynecological pathology with iron replacement therapy were associated with improved hematological outcomes and quality of life.

In conclusion, anemia and gynecological diseases are closely interconnected conditions that require a multidisciplinary and individualized management approach. Timely identification and comprehensive treatment are essential to reduce disease burden and prevent recurrence.

Keywords

Anemia; Iron deficiency anemia; Gynecological diseases; Abnormal uterine bleeding; Uterine fibroids; Women’s healt

PDF

References

  1. World Health Organization. Worldwide prevalence of anaemia 1993–2005: WHO global database on anaemia. Geneva: WHO; 2008.
  2. Camaschella C. Iron-deficiency anemia. N Engl J Med. 2015;372(19):1832–1843.
  3. Kassebaum NJ, et al. A systematic analysis of global anemia burden. Blood. 2014;123(5):615–624.
  4. Munro MG, Critchley HO, Fraser IS. The FIGO classification of causes of abnormal uterine bleeding. Int J Gynaecol Obstet. 2011;113(1):3–13.
  5. Stewart EA. Uterine fibroids. Lancet. 2001;357(9252):293–298.
  6. Fraser IS, Mansour D, Breymann C, Hoffman C, Mezzacasa A. Prevalence of heavy menstrual bleeding and iron deficiency. Int J Gynaecol Obstet. 2015;128(3):196–200.
  7. Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med. 2005;352(10):1011–1023.
  8. Vercellini P, Viganò P, Somigliana E, Fedele L. Endometriosis: Pathogenesis and treatment. Nat Rev Endocrinol. 2014;10(5):261–275.
  9. Auerbach M, Adamson JW. How we diagnose and treat iron deficiency anemia. Am J Hematol. 2016;91(1):31–38.
  10. Pavord S, Daru J, Prasannan N, Robinson S, Stanworth S, Girling J. UK guidelines on the management of iron deficiency in women. Br J Haematol. 2020;188(6):819–830.
  11. Breymann C. Iron deficiency anemia in gynecology and obstetrics. Clin Adv Hematol Oncol. 2015;13(2):S1–S10.

Downloads

Download data is not yet available.