SPECIES OF STREPTOCOCCUS CAUSING CARIES IN CHILDREN AND THEIR LABORATORY DIAGNOSIS

Authors

  • Nafisa Rejametovna Mirvalieva Senior Lecturer at the Department of Microbiology , Virology, and Immunology of Tashkent State Medical University
  • Abbos Azimjon oʻgʻli Arziev Senior Lecturer at the Department of Microbiology , Virology, and Immunology of Tashkent State Medical University
  • Ozodbek Akhrorvich Akbarov Students of the Faculty of Dentistry at Tashkent State Medical University
  • Shakhriyor Farkhod oʻgʻli Maqsudjonov Students of the Faculty of Dentistry at Tashkent State Medical University
  • Abubakr Muzaffar oʻgʻli Arslonov tudents of the Faculty of Dentistry at Tashkent State Medical University
  • Fazliddin Khayrullo oʻgʻli Khabibullaev Students of the Faculty of Dentistry at Tashkent State Medical University

Keywords:

Caries, Streptococcus mutans, Streptococcus sobrinus, biofilm, plaque, demineralization, laboratory diagnostics, PCR, pediatric dentistry, karyogenic bacteria.

Abstract

This article highlights the role of bacteria belonging to the genus Streptococcus, particularly Streptococcus mutans and Streptococcus sobrinus, as the primary etiological factors of dental caries in children. Nowadays, dental caries is thought to be an ecological imbalance in the oral biofilm that causes the hard tissues of the tooth to dissolve. Dental decay has historically been believed to be caused by two species of the Streptococci group: Streptococcus mutans (SM) and Streptococcus sanguinis (SS). The pathogenesis of caries development, biofilm formation mechanisms, and demineralization processes are explained on a scientific basis. Laboratory diagnostic methods—microscopic, bacteriological, biochemical, immunological, and molecular (PCR) methods—are also extensively covered. The importance of assessing the risk of caries and prescribing preventive measures through modern diagnostics is demonstrated. Early detection of this disease in children plays an important role not only in maintaining dental health but also in strengthening overall health. Microbiological control, individual hygiene, and proper nutrition are considered interconnected factors in the prevention of caries.

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References

World Health Organization. Oral health reports and basic methods.

Loesche W.J. Role of Streptococcus mutans in human dental decay.

Fejerskov O., Kidd E. Dental Caries: The Disease and Its Clinical Management.

Selwitz R.H., Ismail A.I., Pitts N.B. Dental caries.

Marsh P.D. Microbial ecology of dental plaque and its significance in health and disease.

Takahashi N., Nyvad B. The role of bacteria in the caries process.

Dewhirst F.E. et al. The human oral microbiome.

Murray P.R., Rosenthal K.S., Pfaller M.A. Medical Microbiology.

Forbes B.A., Sahm D.F., Weissfeld A.S. Bailey and Scott’s Diagnostic Microbiology.

Banas J.A. Virulence properties of Streptococcus mutans.

Bowen W.H., Koo H. Biology of Streptococcus mutans-derived glucosyltransferases.

Krzyściak W. et al. The virulence of Streptococcus mutans and the ability to form biofilms.

Koo H., Falsetta M.L., Klein M.I. The exopolysaccharide matrix and cariogenic biofilm development.

Lamont R.J., Koo H., Hajishengallis G. The oral microbiota: dynamic communities and host interactions.

Beighton D. The complex oral microflora of high-risk individuals and groups and its role in the caries process.

Featherstone J.D.B. Dental caries: a dynamic disease process.

Pitts N.B. Modern concepts of caries measurement and management.

Ten Cate A.R. Oral Histology: Development, Structure and Function.

Berkowitz R.J. Causes, treatment and prevention of early childhood caries.

Pinkham J.R. Pediatric Dentistry: Infancy through Adolescence.

Samaranayake L.P. Essential Microbiology for Dentistry.

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Published

2026-05-26

How to Cite

Nafisa Rejametovna Mirvalieva, Abbos Azimjon oʻgʻli Arziev, Ozodbek Akhrorvich Akbarov, Shakhriyor Farkhod oʻgʻli Maqsudjonov, Abubakr Muzaffar oʻgʻli Arslonov, & Fazliddin Khayrullo oʻgʻli Khabibullaev. (2026). SPECIES OF STREPTOCOCCUS CAUSING CARIES IN CHILDREN AND THEIR LABORATORY DIAGNOSIS. International Multidisciplinary Journal for Research & Development, 13(5), 777–781. Retrieved from https://www.ijmrd.in/index.php/imjrd/article/view/6335