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Vol. 11 No. 09 (2024)
International Multidisciplinary Journal for Research & Development

Articles

CYTOMORPHOLOGICAL CHARACTERISTICS OF THE BONE MARROW IN PATIENTS WITH CHRONIC LEUKEMIA

Published 2024-10-04

  • Madasheva Anazhan Gazkhanovna,Esanova Mukhlisa Eldorzhon kizi,Ravshanova Parviza Ulmas kizi,Abdullaeva Gavkhar Aziz kizi

Madasheva Anazhan Gazkhanovna,Esanova Mukhlisa Eldorzhon kizi,Ravshanova Parviza Ulmas kizi,Abdullaeva Gavkhar Aziz kizi
SamSMU

Abstract

Chronic leukemia involves the abnormal accumulation of mature blood cells in the bone marrow. This study examines the cytomorphological features of bone marrow in chronic lymphocytic leukemia (CLL) and chronic myeloid leukemia (CML). CLL is characterized by small lymphocytes, while CML shows granulocytic hyperplasia with increased eosinophils and basophils. Accurate cytomorphological analysis is crucial for diagnosis, disease monitoring, and treatment decisions in chronic leukemia.

Keywords

Chronic leukemia, bone marrow, cytomorphology, chronic lymphocytic leukemia (CLL), chronic myeloid leukemia (CML), hypercellularity, granulocytic hyperplasia, diagnosis, hematological malignancies.

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References

  1. Bain. B. J., Clark, D. M. (2019). Bone Marrow Pathology (5th ed.). Wiley-Blackwell.
  2. Caligaris-Cappio. F., Hamblin, T. J. (1999). B-cell chronic lymphocytic leukemia: A bird of a different feather. *Journal of Clinical Oncology*, 17(1), 399-408.
  3. Faderl. S., Talpaz. M., Estrov. Z., O’Brien. S., Kurzrock. R., Kantarjian. H. M. (1999). The biology of chronic myeloid leukemia. *The New England Journal of Medicine*, 341(3), 164-172.
  4. Jaffe. E. S., Harris. N. L., Stein. H., Vardiman, J. W. (2001). Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press.
  5. Kwong. Y. L., Wong, K. F. (1997). Haematological cancer in Asia. *Best Practice & Research Clinical Haematology*, 10(2), 1-19.
  6. O’Brien. S., Thomas. D. A., Ravandi. F., Kantarjian, H. M. (2003). Chronic lymphocytic leukemia. *Hematology/Oncology Clinics of North America*, 17(5), 837-858.
  7. Абдиев, К., Махмонов, Л., Мадашева, A., & Маматкулова, Ф. (2021). Business games in teaching hematology. Общество и инновации, 2(6), 208-214
  8. Abdiev, K. M., Makhmonov, L. S., Madasheva, O. G., & Berdiyarova, M. B. The main causes of anemia in patients with diseases of the colon. Scientist Of The XXI Century, 12;
  9. Abdiev K.M, et al. Modern methods of treatment of hemorrhagic syndrome at an early stage in patients with idiopathic thrombocytopenic purpura // Ученый XXI века — 2021, — № 1- 1—P.41–44 (72);
  10. Мадашева, А. Г., & Махмудова, А. Д. (2021). Биохимические показатели у больных гемофилией с мышечными патологиями до и после лечения. Форум молодых ученых, (4 (56)), 233-238.
  11. Gazkhanovna, M. A., Makhmatovich, A. K., & Utkirovich, D. U. (2022). Clinical efficacy of extracorporeal and intravascular hemocorrection methods in psoriasis. ACADEMICIA: An International Multidisciplinary Research Journal, 12(2), 313-318.
  12. Мадашева, А. Г. (2022). Коррекция диффузной алопеции при железодефицитной анемии. Science and Education, 3(12), 231-236.
  13. Мадашева, А. Г. (2022). Клинико-неврологические изменения у больных гемофилией с мышечными патологиями. Science and Education, 3(12), 175-181.
  14. Мадашева, А. Г., & Жураева, М. З. (2019). Биохимические показатели и комплексное лечение больных псориазом с лечебным плазмаферезом. Достижения науки и образования, (10 (51)), 78-82.
  15. Махмудова АН. Правовая защита пациентов в сфере здравоохраения в новом Узбекистане. Academic research in educational sciences. 2022(1):102-7.
  16. Махмудова АН, Махмудова С. Гуманитаризация медицинского образования как фактор повышения качества обучения в вузе. Science and Education. 2022;3(6):709-18.]
  17. O’tayev ST, Mahmudova AN. O’zbekiston Respublikasining sog’liqni saqlash tizimida hozirgi kunda neyroxirurgiya yutuqlari. Science and Education. 2023;4(2):190-4.

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