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Vol. 12 No. 03 (2025)
International Multidisciplinary Journal for Research & Development

Articles

THE BENEFICIAL EFFECTS OF CORN SILK (ZEA MAYS) IN GALLSTONE DISEASE

Published 2025-03-14

  • Mamatova Irodakhon Yusupovna, Madaminova Gulasal Abdurauf kizi

Mamatova Irodakhon Yusupovna, Madaminova Gulasal Abdurauf kizi
Department of Biological Chemistry, Andijan State Medical Institute, Andijan, Uzbekistan

Abstract

Gallstone disease (cholelithiasis) is a common biliary disorder affecting millions worldwide. Conventional treatments such as surgery and medication often come with risks and side effects, leading to increased interest in natural remedies. Corn silk (Zea mays L.) is a traditional herbal remedy widely used for its diuretic, anti-inflammatory, and choleretic properties [1]. This review explores the potential therapeutic effects of corn silk in gallstone disease, including its ability to improve bile secretion, reduce inflammation, and prevent gallstone formation [2].

Various bioactive compounds, including flavonoids, tannins, polysaccharides, and alkaloids, contribute to corn silk’s medicinal properties. Scientific studies have demonstrated its hepatoprotective effects, bile flow stimulation, and antioxidant activity, which may help dissolve gallstones and prevent their recurrence [3]. However, more clinical trials are needed to confirm its efficacy in human subjects. This paper provides an overview of the mechanisms, experimental findings, and future directions for using corn silk in gallstone disease management [4].

Keywords

Corn silk, Zea mays, gallstone disease, cholelithiasis, bile secretion, hepatoprotection, anti-inflammatory.

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