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Vol. 12 No. 10 (2025)
International Multidisciplinary Journal for Research & Development

Articles

CRISPR AND GENE EDITING: REVOLUTIONIZING TREATMENT OF GENETIC DISORDERS

Published 2025-10-30

  • Olishova Risolat Abduvali qizi

Olishova Risolat Abduvali qizi
Andijan State Institute of Technology Faculty of Biomedical Engineering 3nd-year student

Abstract

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and gene editing technologies have emerged as groundbreaking tools in modern biomedical research, offering unprecedented precision in modifying genetic material. These technologies enable targeted correction of disease-causing mutations, paving the way for the treatment of previously incurable genetic disorders such as cystic fibrosis, sickle cell anemia, and Duchenne muscular dystrophy. This article explores the molecular mechanisms of CRISPR-Cas9, recent advancements in gene editing approaches, and their clinical applications. Furthermore, it highlights ethical considerations, safety challenges, and the potential of these technologies to transform personalized medicine. The findings suggest that CRISPR and gene editing not only offer therapeutic hope for patients with genetic disorders but also represent a paradigm shift in the field of regenerative medicine and biomedical innovation.

Keywords

CRISPR, gene editing, genetic disorders, Cas9, personalized medicine, regenerative medicine, molecular biology, biotechnology, ethical considerations, clinical applications.

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References

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