PREDICTION OF REPRODUCTIVE DISORDERS IN WOMEN WITH ENDOMETRITIS

Abstract
The review outlines the main role of chronic endometritis in the genesis of reproductive disorders in women. Etiological risk factors for the development and trigger mechanism of chronic inflammatory processes in the endometrium, features of the pathogenesis and clinical picture of chronic endometritis have been identified. The importance of diagnosing chronic endometritis using the immunohistochemical method, the feasibility of immunohistochemical research to assess receptor expression and the severity of local immunity in the endometrium, and the need to determine the alpha-2-microglobulin fertility protein (AMGF) to predict reproductive disorders are shown.
Keywords
Infertility, receptor expression, chronic endometritis, alpha-2-microglobulin.
References
- Zdanovsky, V. M. Results of the use of assisted reproductive technologies in infertile patients with endometrial pathology / V. M. Zdanovsky, N. B. Buravchenko // Russian Bulletin of Obstetrician-Gynecologist. - 2010. - No. 2. - P. 39–42.
- Gombolevskaya, N. A. Modern criteria for the diagnosis of chronic endometritis (literature review) / N. A. Gombolevskaya, L. A. Marchenko // Problems of reproduction. - 2012. - T. 18, No. 1. - P. 42–46.
- The role of specific immunohistochemical techniques in the diagnosis of chronic endometritis / V. A. Kolmyk [et al.] // Bulletin of the Russian Military Medical Academy. — 2015. —No. 1(49). — pp. 34–37.
- Tabolova, V.K. The influence of chronic endometritis on the outcomes of assisted reproductive technology programs: morpho-functional and molecular genetic features / V.K. Tabolova, I.E. Korneeva // Obstetrics and Gynecology. — 2013. — No. 10. — pp. 17–22.