THE EFFECTS OF CERTAIN D-BLOCK METALS ON THE HUMAN BODY: A CASE STUDY OF COPPER
Abstract
This article provides an extensive overview of copper, a d-block metal, and its role in human health. It explores the physical and chemical characteristics of copper, its distribution in natural sources, industrial applications, and biological significance. The study discusses how copper enters the human body and the negative health effects of its deficiency or excess accumulation. Particular attention is paid to diseases linked to copper, including damage to the kidneys and liver, hemolysis, and jaundice. Additionally, cases of copper poisoning in South Asian countries (India, Bangladesh, Pakistan) are analyzed statistically. The findings highlight the need to consume copper in controlled and safe amounts.
Keywords
copper, isotopes, poisoning, kidney failure, drinking water, biological role, health, food.
References
- Georgopoulos, P.G., Roy, A., Yonone-Lioy, M.J., et al., 2001. J. Toxicol. Environ. Health 4, 341e394.
- Roman Viñas, B., Barba, L.R., Ngo, J., et al., 2011. Ann. Nutr. Metab. 59, 84e95.
- Romana, D.L., de, Olivares, M., Uauy, R., et al., 2011. J. Trace Elem. Med. Biol. 25, 3e13.
- Priya, S., 2018. Indian J. Med. Special. 9 (3), 140e142.
- Trumbo, P., Yates, A.A., Schlicker, S., et al., 2001. J. Am. Diet. Assoc. 101, 294e301.
- Ahasan, H.A.M.N., Chowdhury, M.A.J., Azhar, M.A., et al., 1994. Trop. Doct. 24, 52e53.
- Naha, K., Saravu, K., Shastry, B.A., 2012. Clin. Toxicol. 50, 197e201.
- Myint, ZW, Oo, TH, Thein, KZ et al. Enn Hematol 97 , 1527–1534 (2018). https://doi.org/10.1007/s00277-018-3407-5
- Merico, D., Spickett, C., O’Hara, M. et al. ATP7B variant c.1934T > G p.Met645Arg causes Wilson disease by promoting exon 6 skipping. npj Genom. Med. 5, 16 (2020). https://doi.org/10.1038/s41525-020-0123-6