THE IMPACT OF TYPE 2 DIABETES ON CARDIAC ARRHYTHMIAS IN ELDERLY PATIENTS DURING THE SUBACUTE PHASE OF MYOCARDIAL INFARCTION: A CLINICAL AND METABOLIC CORRELATION STUDY

Authors

  • Hamroyeva Madinabonu Yo‘ldosh kizi Bukhara State Medical Institute Assistant at the Department of Faculty and Hospital Therapy

Keywords:

Type 2 Diabetes Mellitus, Myocardial Infarction, Arrhythmias, Glycemic Control, Diabetic Nephropathy, Elderly Patients, Hyperglycemia, HbA1c, Metabolic Factors, Cardiovascular Disease.

Abstract

 Type 2 diabetes mellitus (T2DM) is a growing medical-social problem, characterized by widespread prevalence, increasing incidence, and serious complications. The combination of micro- and macrovascular complications in T2DM leads to early disability and death. The disease is often accompanied by atherosclerosis, resulting in lipid and carbohydrate metabolism disturbances, hypercholesterolemia, hypertriglyceridemia, and low levels of high-density lipoproteins. T2DM promotes the development of cardiovascular issues, including arrhythmias, particularly during the acute period of myocardial infarction (MI). The research aims to explore the prevalence and correlation of arrhythmias in elderly patients with MI and diabetes, highlighting the role of metabolic factors such as glycemic control and kidney function in arrhythmia development. The study found that the incidence of arrhythmias was higher in patients with T2DM, with significant correlations to age, diabetes duration, glycemic control, and the presence of diabetic nephropathy. Moreover, the study revealed a U-shaped relationship between the frequency of arrhythmias and HbA1c levels. These findings suggest that optimal management of diabetes and early detection of arrhythmias can improve outcomes in elderly patients with MI.

Downloads

Download data is not yet available.

References

Hamroyeva M.Y., St Элевацияли Миокард Инфарктида Шифохонагача Тизимли Тромболиз Муаммолари Ва Уларнинг Ечими. Miasto Przyszłości. Vol. 49 (2024):420-431

Hamroyeva M.Y., St Сегмент Элевацияли Ўткир Коронар Синромда Шифохонагача Тизимли Тромболизисни Чап Қоринча Систолик Дисфункциясига Таъсири. Miasto Przyszłości. Vol. 49 (2024):376-381

World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus. Geneva: WHO; 1999.

Niposayeva E.S., Aronov D.M. Rehabilitation of patients after myocardial infarction: differentiated approaches. Therapeutic Archive. 1998;5:42–45. [in Russian]

American Diabetes Association. Standards of medical care in diabetes—2024. Diabetes Care. 2024;47(Suppl 1):S1–S204. https://doi.org/10.2337/dc24-S001

Kannel W.B., Wilson P.W. Risk factors that attenuate the female coronary disease advantage. Arch Intern Med. 1995;155(1):57–61. https://doi.org/10.1001/archinte.1995.00430010061008

Fagherazzi G, El Fatouhi D, Belhadi A, et al. Heart rhythm disorders and glycemic variability in type 2 diabetes: pathophysiology and clinical perspectives. Cardiovasc Diabetol. 2020;19(1):123. https://doi.org/10.1186/s12933-020-01094-1

Ritz E, Rychlík I, Locatelli F, Halimi S. End-stage renal failure in type 2 diabetes: a medical catastrophe of worldwide dimensions. Am J Kidney Dis. 1999;34(5):795–808. https://doi.org/10.1016/S0272-6386(99)70041-1

Vinik A.I., Ziegler D. Diabetic cardiovascular autonomic neuropathy. Circulation. 2007;115(3):387–397. https://doi.org/10.1161/CIRCULATIONAHA.106.634949

Gu K, Cowie C.C., Harris M.I. Mortality in adults with and without diabetes in a national cohort of the U.S. population, 1971–1993. Diabetes Care. 1998;21(7):1138–1145. https://doi.org/10.2337/diacare.21.7.1138

Downloads

Published

2025-06-15

How to Cite

Hamroyeva Madinabonu Yo‘ldosh kizi. (2025). THE IMPACT OF TYPE 2 DIABETES ON CARDIAC ARRHYTHMIAS IN ELDERLY PATIENTS DURING THE SUBACUTE PHASE OF MYOCARDIAL INFARCTION: A CLINICAL AND METABOLIC CORRELATION STUDY. International Multidisciplinary Journal for Research & Development, 12(06). Retrieved from https://www.ijmrd.in/index.php/imjrd/article/view/3370