IATROGENESIS IN MEDICAL PRACTICE: CAUSES, TYPES, AND PREVENTION STRATEGIES

Authors

Muhammadiyeva Kamola Furqat qizi Student of EMU University

Keywords:

iatrogenesis, patient safety, medical errors, adverse events, drug side effects, prevention strategies, healthcare quality, safety culture.

Abstract

This article scientifically examines the problem of iatrogenesis in medical practice-harmful conditions arising in patients as a direct result of the treatment process itself. The paper provides a comparative analysis of the primary types of iatrogenesis (medication-related, surgical, diagnostic, infectious, and psychogenic), their underlying causes, and prevalence rates across various countries. Furthermore, the article evaluates internationally proven prevention strategies, including standardized clinical protocols, safety culture, and digital monitoring systems, to develop practical recommendations for the healthcare system of Uzbekistan.

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References

Aspden, P., Corrigan, J. M., Wolcott, J., & Erickson, S. M. (Eds.). (2004). Patient safety: Achieving a new standard for care. National Academies Press. https://doi.org/10.17226/10863

Bates, D. W., Levine, D. M., Salmasian, H., Syrowatka, A., Shahian, D. M., Lipsitz, S., Zebrowski, J. P., Myers, L. C., Logan, M. S., Roy, C. G., Iannaccone, C., Frits, M. L., Volk, L. A., Fiskio, J. M., Sato, L., Acker, W., Schiff, G. D., & Wynia, M. K. (2021). The safety of inpatient health care. New England Journal of Medicine, 385(20), 1837–1847. https://doi.org/10.1056/NEJMsa2103879

Brennan, T. A., Leape, L. L., Laird, N. M., Hebert, L., Localio, A. R., Lawthers, A. G., Newhouse, J. P., Weiler, P. C., & Hiatt, H. H. (1991). Incidence of adverse events and negligence in hospitalized patients: Results of the Harvard Medical Practice Study I. New England Journal of Medicine, 324(6), 370–376. https://doi.org/10.1056/NEJM199102073240604

Chen, Y., Wang, Y., Zhang, H., & Liu, J. (2023). Understanding the effects of iatrogenic management on population health: A medical innovation perspective. China CDC Weekly, 5(27). https://doi.org/10.46234/ccdcw2023.118

Davis, P., Lay-Yee, R., Briant, R., Ali, W., Scott, A., & Schug, S. (2002). Adverse events in New Zealand public hospitals I: Occurrence and impact. New Zealand Medical Journal, 115(1167), U271.

Tursunaliyevich, F. N. (2023). Sharofiddinovich SS Barqaror Rivojlanishni Maktabgacha Ta'lim Yoshidagi Bolalarga Singdirish. Journal of Science, Research and Teaching, 2(2), 26-29.

Nasriyev, F. T., & Qobilov, F. S. o‘g‘li. (2023). Aholiga uchraydigan mavsumiy va virus kasalliklarni oldini olishda global oziq-ovqat iste’moli va ishlab chiqarilishidagi muammo. Umidli kimyogarlar–2023: XXXIII ilmiy-texnikaviy anjumani maqolalar to‘plami, 12(440), 880. https://doi.org/10.5281/zenodo.7895680

European Centre for Disease Prevention and Control. (2022). Healthcare-associated infections: Burden of healthcare-associated infections in Europe. ECDC. https://www.ecdc.europa.eu/en/healthcare-associated-infections

Haynes, A. B., Weiser, T. G., Berry, W. R., Lipsitz, S. R., Breizat, A. H., Dellinger, E. P., Herbosa, T., Joseph, S., Kibatala, P. L., Lapitan, M. C., Merry, A. F., Moorthy, K., Reznick, R. K., Taylor, B., & Gawande, A. A. (2009). A surgical safety checklist to reduce morbidity and mortality in a global population. New England Journal of Medicine, 360(5), 491–499. https://doi.org/10.1056/NEJMsa0810119

Joint Commission. (2023). Sentinel event data: Root causes by event type 2004–2022. The Joint Commission. https://www.jointcommission.org/resources/patient-safety-topics/sentinel-event

Kohn, L. T., Corrigan, J. M., & Donaldson, M. S. (Eds.). (2000). To err is human: Building a safer health system. National Academies Press. https://doi.org/10.17226/9728

Leape, L. L., Brennan, T. A., Laird, N., Lawthers, A. G., Localio, A. R., Barnes, B. A., Hebert, L., Newhouse, J. P., Weiler, P. C., & Hiatt, H. (1991). The nature of adverse events in hospitalized patients: Results of the Harvard Medical Practice Study II. New England Journal of Medicine, 324(6), 377–384. https://doi.org/10.1056/NEJM199102073240605

Morgan, D. J., Dhruva, S. S., Wright, S. M., & Korenstein, D. (2015). 2015 update on medical overuse. JAMA Internal Medicine, 176(1), 120–121. https://doi.org/10.1001/jamainternmed.2015.6525

Panagioti, M., Khan, K., Keers, R. N., Abuzour, A., Phipps, D., Kontopantelis, E., Bower, P., Campbell, S., Haneef, R., Avery, A. J., & Ashcroft, D. M. (2019). Prevalence, severity, and nature of preventable patient harm across medical care settings: Systematic review and meta-analysis. BMJ, 366, l4185. https://doi.org/10.1136/bmj.l4185

Peer, R., & Shabir, N. (2018). Iatrogenesis: A review on nature, extent, and distribution of healthcare hazards. Journal of Family Medicine and Primary Care, 7(2), 309–314. https://doi.org/10.4103/jfmpc.jfmpc_329_17

Rafter, N., Hickey, A., Conroy, R. M., Condell, S., O'Connor, P., Vaughan, D., Walsh, G., & Williams, D. J. (2015). The Irish National Adverse Events Study (INAES): The frequency and nature of in-hospital adverse events. BMJ Quality & Safety, 26(2), 111–119. https://doi.org/10.1136/bmjqs-2015-004846

Reason, J. (2000). Human error: Models and management. BMJ, 320(7237), 768–770. https://doi.org/10.1136/bmj.320.7237.768

Schioler, T., Lipczak, H., Pedersen, B. L., Mogensen, T. S., Bech, K. B., Stockmarr, A., Svenning, A. R., & Frølich, A. (2001). Incidence of adverse events in hospitals: A retrospective study of medical records. Ugeskrift for Laeger, 163(39), 5370–5378.

Stelfox, H. T., Palmisani, S., Scurlock, C., Orav, E. J., & Bates, D. W. (2006). The "To Err Is Human" report and the patient safety literature. Quality and Safety in Health Care, 15(3), 174–178. https://doi.org/10.1136/qshc.2006.017947

Vincent, C., Neale, G., & Woloshynowych, M. (2001). Adverse events in British hospitals: Preliminary retrospective record review. BMJ, 322(7285), 517–519. https://doi.org/10.1136/bmj.322.7285.517

Wilson, R. M., Runciman, W. B., Gibberd, R. W., Harrison, B. T., Newby, L., & Hamilton, J. D. (1995). The quality in Australian health care study. Medical Journal of Australia, 163(9), 458–471. https://doi.org/10.5694/j.1326-5377.1995.tb124691.x

World Health Organization. (2019). Patient safety: Global action on patient safety. World Health Assembly Resolution WHA72.6. WHO Press. https://www.who.int/teams/integrated-health-services/patient-safety

World Health Organization. (2024). Global patient safety report 2024. WHO Press. https://iris.who.int/handle/10665/376928

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Published

2026-02-23

How to Cite

Muhammadiyeva Kamola Furqat qizi. (2026). IATROGENESIS IN MEDICAL PRACTICE: CAUSES, TYPES, AND PREVENTION STRATEGIES. International Multidisciplinary Journal for Research & Development, 13(02), 660–666. Retrieved from https://www.ijmrd.in/index.php/imjrd/article/view/5158