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SYNTHESIS OF HISTIDINE DERIVATIVE WITH SUCCINIC ACID AND STUDY OF ITS PHYSICOCHEMICAL PROPERTIES

Abstract

Histidine molecule has an amine group, a carboxyl group and an imidazole ring. This structure determines its physical and chemical properties. In histidine, the ring of heterocyclic amine imidazole is a basic group, which also shows the aromaticity of histidine. Histidine is one of the natural compounds, the source of the reagent provides an opportunity to obtain various supramolecular complexes based on reversible and heterocyclic compounds and to study their biological activity and stability. Histidine (H) and its derivatives are important in the formation of complexes, and it is histidine (H) and formation of complexes with its derivatives and the study of the stability of the formed complexes is important for the good growth and development of living organisms, especially the fact that it is important for the good assimilation of microelements in plants and animals increases its relevance.

In our research, complexes of histidine (H) and succinic acid with different ratios were obtained and some physicochemical parameters were studied.

Keywords

Succinic acid, histidine, amino acid, dicarboxylic acid ninhydrin test, chromatography, IR spectroscopy, histamine.

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