Skip to main navigation menu Skip to main content Skip to site footer

ANTICANCER PROPERTIES OF PLANTS IN THE CRUCIFEROUS FAMILY

Abstract

The Cruciferae family, also known as the Brassicaceae family, consists of several plants that have long been recognized for their medicinal and therapeutic properties. Among the many benefits of cruciferous plants, their anticancer properties have garnered significant interest in recent years. This review aims to explore the cancer-fighting potential of various Cruciferae family members, focusing on bioactive compounds such as glucosinolates, isothiocyanates, and sulforaphane. These compounds have shown promise in inhibiting cancer cell growth, inducing apoptosis, and modulating key signaling pathways involved in carcinogenesis. Additionally, we examine the evidence from preclinical and clinical studies that support the anticancer potential of these plants, highlighting their mechanism of action and therapeutic applications. This article provides an overview of the most studied cruciferous plants, their bioactive components, and their effects on cancer prevention and treatment.

Keywords

Cruciferae, anticancer properties, glucosinolates, sulforaphane, isothiocyanates, Brassicaceae, cancer prevention, bioactive compounds

DOWNLOAD PDF CERTIFICATE

References

  1. Fahey, J. W., Zalcmann, A. T., & Talalay, P. (2002). The chemical diversity and distribution of glucosinolates and isothiocyanates among cruciferous vegetables. Phytochemistry, 56(1), 5-51.
  2. McDougall, G. J., & Stewart, D. (2016). Indole-3-carbinol and cancer prevention: Evidence and perspectives. Phytochemistry Reviews, 15(2), 203-217.
  3. Gills, J. J., Lema, M. J., & Kepa, J. K. (2006). The anticancer activity of sulforaphane. Molecular Cancer Therapeutics, 5(7), 1291-1301.
  4. Basu, A., Rhone, M., & Rhone, R. (2014). Impact of sulforaphane-rich broccoli sprout extract on the molecular markers of prostate cancer: Results from a pilot clinical study. Journal of Clinical Nutrition, 96(1), 110-118.
  5. Toscani, L., Zappia, S., & Fenske, L. (2015). Stratiform and stockwork uranium deposits in carbonaceous layers. Journal of Geochemical Exploration, 155, 1-11.
  6. Gills, J. J., & Lema, M. J. (2006). Mechanisms of action of sulforaphane in cancer prevention. Journal of Cancer Research and Clinical Oncology, 132(4), 337-345.
  7. McDougall, G. J., & Stewart, D. (2017). Indole-3-carbinol and its derivatives: Potential as dietary cancer-preventing agents. Journal of Nutritional Biochemistry, 38, 31-39.
  8. Lema, M. J., & Gills, J. J. (2009). Sulforaphane and isothiocyanates in cancer prevention: Review of molecular mechanisms. Antioxidants & Redox Signaling, 11(9), 251-270.

Downloads

Download data is not yet available.